ZEISS Lattice Lightsheet 7

Long-Term Volumetric Imaging of Living Cells

ZEISS Lattice Lightsheet 7 makes light sheet fluorescence microscopy available for live cell imaging at subcellular resolution – while also allowing you to use your standard sample carriers. With this automated, easy-to-use system, volumetric imaging of subcellular structures and dynamics over hours and days with best protection from photo damage becomes available to everyone. Discover the dynamics of life in unprecedented depth of detail – with the ease you never imagined possible!

Lattice Light Sheet Technology Made Accessible to Everyone

The importance of gentle light sheet imaging at high resolution cannot be overestimated for the study of subcellular processes. With Lattice Lightsheet 7, ZEISS makes access to the benefits of this advanced technology amazingly simple. Without having to adapt your usual sample preparation, you can examine living specimens directly on the standard sample carriers you already use for confocal microscopy. Complex alignment processes are performed automatically in this system so that you can focus your full attention on your experiments.


  • EExamine living specimens directly on your standard sample carriers
  • EWatch the subcellular dynamics of life over hours and even days
  • EReveal three-dimensional details in their true proportions
  • EFocus your full attention on your experiments

Next to No Phototoxicity and Bleaching

You want to watch the dynamics of life at subcellular resolution to study how the finest structures change over time. But your conventional imaging systems quickly reach their limits because they are too invasive and destroy what you are observing. Instead, ZEISS Lattice Lightsheet 7 provides lattice-structured light that automatically adapts to your sensitive samples, resulting in a massive reduction of photobleaching and phototoxicity, to allow your experiments to continue over hours and even days. The controlled incubation environment and an integrated auto-immersion mechanism enable unattended long-term experiments.

High-speed Volumetric Imaging

The extremely fast image acquisition of ZEISS Lattice Lightsheet 7 enables up to three volume scans per second. Dynamic imaging of full sample volumes with this high temporal resolution means no longer missing an interesting event on your coverslip. Near-isotropic resolution along the X, Y and Z axes gives you a three-dimensional image of your sample that reveals structural details in their true proportions. Fast laser switching allows for imaging using up to three colors practically simultaneously, with minimized color crosstalk.