Tomocube HT-X1 mini
Compact, modular holotomography system delivering high-resolution, label-free 3D live-cell imaging
The TomoCube HT-X1 mini is a compact, benchtop holotomography system designed for high-resolution, label-free 3D live-cell imaging. It employs the same advanced second-generation optical diffraction tomography technology as Tomocube’s flagship HT-X1, allowing researchers to capture detailed cellular structures and dynamics without staining or phototoxicity. Its modular and upgradeable design supports add-ons like fluorescence imaging, environmental control, and multi-wavelength illumination, making it adaptable for diverse research applications. The system integrates seamlessly with TomoAnalysis™ software, providing powerful AI-driven quantitative tools for analyzing cell morphology, volume, and organelle composition. Ideal for labs with limited space, the HT-X1 mini delivers the precision of a full-scale holotomography platform in a streamlined, space-efficient form.
Tomocube HT-X1 mini Specifications
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Dimensions: 430 mm (W) × 526 mm (D) × 492 mm (H)
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Weight: approx. 30 kg
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Power supply: 100-240 VAC, 50/60 Hz, 5-3 A
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Stage travel range: 85 × 60 mm
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Objective lens: 40×, NA 0.75 (air)
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Objective working distance: 510 µm
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Condenser lens: NA 0.72
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Image sensor: 2.8 Megapixel CMOS
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Field-of-view: 218 µm × 165 µm
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Compatible labware: TomoDish 35 mm / 50 mm, microscopic slide (#1.5 bottom thickness), chamber slide (#1.5)
Holotomography Optics
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Light source: LED
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Illumination wavelengths: 444 nm standard, 520 nm & 660 nm optional
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Axial scan range: 31 µm, 62 µm, 146 µm (for bacteria, cells, organoids respectively)
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Minimum acquisition speed: ~1.3 s per image
Optional Modules
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Fluorescence Light Engine (optional): 3-channel LED with excitation filters 378/52 nm, 474/27 nm, 554/23 nm; emission filters 432/36 nm, 515/30 nm, 595/31 nm
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Laser-assisted autofocus (optional)
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Environmental Controller (optional): Dimensions 110 × 208 × 206 mm, weight 3.8 kg, supports temperature control (30-40 °C), CO₂ 5-20 % and humidity 5-20 %
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For further information, it is recommended to reach out to a representative from Nuhsbaum. Our representatives are knowledgeable about the Tomocube HT-X1 mini offerings and can provide expert guidance and support in selecting the right configuration to meet specific research needs.
Tomocube HT-X1 mini Description
The HT-X1 mini is designed to bring advanced 3D holotomography imaging into more everyday-lab environments. It features a compact footprint (430 mm × 526 mm × 492 mm) and a weight around 30 kg, making it suitable for standard lab benches or even shared facilities. It uses the same second-generation holotomography technology as the larger HT-X1 series, enabling high-resolution, label-free 3-D live-cell imaging without the need for dyes or extensive sample preparation.
In terms of optics and performance, the HT-X1 mini comes with a 40×, NA 0.75 air objective, a 2.8-megapixel CMOS sensor, and an LED illumination system (444 nm standard, with optional 520 nm and 660 nm wavelengths) for holotomographic imaging. The system supports an imaging field of view of 218 µm × 165 µm, a stage travel of 85 × 60 mm, and a minimum acquisition speed of about 1.3 seconds per image in holotomography mode.
What makes the HT-X1 mini especially flexible is its modularity. You can start with the basic holotomography core and then add optional modules such as fluorescence imaging (3-channel), a laser-based autofocus unit, multi-wavelength illumination, and an environmental incubation chamber for live-cell time-lapse experiments. This expandability means the system can grow alongside your research needs, offering a cost-effective entry point without sacrificing quality or future capability.
For further information, it is recommended to reach out to a representative from Nuhsbaum. Our representatives are knowledgeable about the Tomocube HT-X1 mini offerings and can provide expert guidance and support in selecting the right configuration to meet specific research needs.
